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Npn-2 Protein

《英文msh詞典》Npn-2 Protein
[入口詞] Npn-2 Protein
[主題詞] Neuropilin-2
[英文釋義] Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS,which alters the binding characteristics of the receptor.